Cardiovascular biomarkers in patients with acute decompensated heart failure randomized to sacubitril-valsartan or enalapril in the PIONEER-HF trial

AIMS: Circulating high-sensitivity cardiac troponin (hsTn) and soluble ST2 (sST2) reflect myocardial stress in patients with heart failure (HF). Production of cyclic guanosine 3′5′ monophosphate (cGMP) in response to activation of natriuretic peptide receptors reduces cardiac afterload and preload....

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Publicat a:Eur Heart J
Autors principals: Morrow, David A, Velazquez, Eric J, DeVore, Adam D, Prescott, Margaret F, Duffy, Carol I, Gurmu, Yared, McCague, Kevin, Rocha, Ricardo, Braunwald, Eugene
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Fast Track Clinical Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801941/
https://ncbi.nlm.nih.gov/pubmed/31093657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz240
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