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Cardiovascular biomarkers in patients with acute decompensated heart failure randomized to sacubitril-valsartan or enalapril in the PIONEER-HF trial

AIMS: Circulating high-sensitivity cardiac troponin (hsTn) and soluble ST2 (sST2) reflect myocardial stress in patients with heart failure (HF). Production of cyclic guanosine 3′5′ monophosphate (cGMP) in response to activation of natriuretic peptide receptors reduces cardiac afterload and preload....

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Detalhes bibliográficos
Publicado no:Eur Heart J
Main Authors: Morrow, David A, Velazquez, Eric J, DeVore, Adam D, Prescott, Margaret F, Duffy, Carol I, Gurmu, Yared, McCague, Kevin, Rocha, Ricardo, Braunwald, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801941/
https://ncbi.nlm.nih.gov/pubmed/31093657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehz240
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