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Replication Stress at Telomeric and Mitochondrial DNA: Common Origins and Consequences on Ageing
Senescence is defined as a stress-induced durable cell cycle arrest. We herein revisit the origin of two of these stresses, namely mitochondrial metabolic compromise, associated with reactive oxygen species (ROS) production, and replicative senescence, activated by extreme telomere shortening. We di...
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| Yayımlandı: | Int J Mol Sci |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
MDPI
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6801922/ https://ncbi.nlm.nih.gov/pubmed/31597307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194959 |
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