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Conditional Knockdown of Osteopontin Inhibits Breast Cancer Skeletal Metastasis

High osteopontin (OPN) expression is linked to breast cancer bone metastasis. In this study we modulated osteopontin levels conditionally and investigated any related antineoplastic effects. Therefore, we established cell clones from human breast cancer MDA-MB-231 cells, in which the expression of O...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kovacheva, Marineta, Zepp, Michael, Schraad, Muriel, Berger, Stefan, Berger, Martin R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801824/
https://ncbi.nlm.nih.gov/pubmed/31590218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194918
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