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Structure and Dynamics of Mono- vs. Doubly Lipidated Rab5 in Membranes

The Rab5 small GTPase is a regulator of endosomal trafficking and vesicle fusion. It possesses two adjacent cysteine residues for post-translational geranylgeranylation at its C-terminus for the protein to associate with the early endosome membrane. We compare the effect of mono-lipidification of on...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Münzberg, Eileen, Stein, Matthias
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801778/
https://ncbi.nlm.nih.gov/pubmed/31561436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20194773
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