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Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of Parkinsonism

Sleep complaints are an early clinical symptom of neurodegenerative disorders. Patients with Parkinson’s disease (PD) experience sleep disruption (SD). The objective of this study was to determine if pre-existing, chronic SD leads to a greater loss of tyrosine hydroxylase (TH) within the striatum an...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Xu, Mo, Bohlen, Jerry K., Moore, Cynthia, Nipper, Michelle A., Finn, Deborah A., Jones, Carolyn E., Lim, Miranda M., Meshul, Charles K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801095/
https://ncbi.nlm.nih.gov/pubmed/31535395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24520
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