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Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae

Neisseria gonorrhoeae, the sole causative agent of gonorrhea, constitutively undergoes diversification of the type IV pilus. Gene conversion occurs between one of several donor silent copies located in distinct loci and the recipient pilE gene, encoding the major pilin subunit of the pilus. A guanin...

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Publicat a:Mol Microbiol
Autors principals: Prister, Lauren L, Ozer, Egon A, Cahoon, Laty A, Seifert, H Steven
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800796/
https://ncbi.nlm.nih.gov/pubmed/31338863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14356
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