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An Alternative DNA Structure is Necessary for Pilin Antigenic Variation in Neisseria gonorrhoeae

Pathogens can utilize DNA recombination to promote antigenic variation of surface structures to avoid immune detection. We identified a cis-acting DNA sequence near the antigenically variable pilin locus of the human pathogen, Neisseria gonorrhoeae. This 16 base pair G-rich sequence was required for...

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Hlavní autoři: Cahoon, Laty A., Seifert, H. Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803317/
https://ncbi.nlm.nih.gov/pubmed/19661435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175653
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