Chemical induction of aminoglycoside uptake overcomes antibiotic tolerance and resistance in Staphylococcus aureus

Aminoglycoside antibiotics require proton motive force (PMF) for bacterial internalization. In non-respiring populations, PMF drops below the level required for drug influx, limiting the utility of aminoglycosides against strict and facultative anaerobes. We recently demonstrated that rhamnolipids (...

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Detaylı Bibliyografya
Yayımlandı:Cell Chem Biol
Asıl Yazarlar: Radlinski, Lauren C., Rowe, Sarah E., Brzozowski, Robert, Wilkinson, Alec D., Huang, Rennica, Eswara, Prahathees, Conlon, Brian P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800641/
https://ncbi.nlm.nih.gov/pubmed/31402316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.07.009
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