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The NLRP1 inflammasome: new mechanistic insights and unresolved mysteries

Nucleotide-binding domain, leucine-rich repeat (NLR) proteins constitute a diverse class of innate immune sensors that detect pathogens or stress-associated stimuli in plants and animals. Some NLRs are activated upon direct binding to pathogen-derived ligands. In contrast, we focus here on a vertebr...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Mitchell, Patrick S., Sandstrom, Andrew, Vance, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800612/
https://ncbi.nlm.nih.gov/pubmed/31121538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2019.04.015
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