Tanshinone I Inhibits IL-1β-Induced Apoptosis, Inflammation And Extracellular Matrix Degradation In Chondrocytes CHON-001 Cells And Attenuates Murine Osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a prevalent degenerative joint disease, which was characterized by inflammation and cartilage degradation. Accumulating evidence has demonstrated that Tanshinone I has an anti-inflammatory effect in various diseases. However, the efficacy of Tanshinone I as an anti-...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Wang, Xipeng, Fan, Jianbo, Ding, Xiaomin, Sun, Yuyu, Cui, Zhiming, Liu, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800556/
https://ncbi.nlm.nih.gov/pubmed/31686786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S216596
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