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MALDI-MS: a Rapid and Reliable Method for Drug-to-Antibody Ratio Determination of Antibody-Drug Conjugates
BACKGROUND: It is believed that the loading value of anticancer drug conjugated to the monoclonal antibody, called drug-to-antibody ratio (DAR), is the main quality feature of antibody-drug conjugates. METHODS: In this study, matrix assisted laser desorption/ionization mass spectrometry was used to...
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| Publicat a: | Iran Biomed J |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Pasteur Institute of Iran
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800535/ https://ncbi.nlm.nih.gov/pubmed/31104399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.29252/ibj.23.6.395 |
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