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Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei

Multiprotein editosomes catalyze gRNA-specified insertion and deletion of uridines to create functional mitochondrial mRNAs in Trypanosoma brucei. Three functionally distinct editosomes are distinguished by their single KREN1, KREN2, or KREN3 RNase III endonuclease and, respectively, KREPB8, KREPB7,...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:RNA
Prif Awduron: McDermott, Suzanne M., Carnes, Jason, Stuart, Kenneth
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800513/
https://ncbi.nlm.nih.gov/pubmed/31171708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071258.119
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