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Editosome RNase III domain interactions are essential for editing and differ between life cycle stages in Trypanosoma brucei

Multiprotein editosomes catalyze gRNA-specified insertion and deletion of uridines to create functional mitochondrial mRNAs in Trypanosoma brucei. Three functionally distinct editosomes are distinguished by their single KREN1, KREN2, or KREN3 RNase III endonuclease and, respectively, KREPB8, KREPB7,...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: McDermott, Suzanne M., Carnes, Jason, Stuart, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800513/
https://ncbi.nlm.nih.gov/pubmed/31171708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.071258.119
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