Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

Genome editing using the CRISPR/Cas9 system has been used to make precise heritable changes in the DNA of organisms. Although the widely used Streptococcus pyogenes Cas9 (SpCas9) and its engineered variants have been efficiently harnessed for numerous gene-editing applications across different platf...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Acharya, Sundaram, Mishra, Arpit, Paul, Deepanjan, Ansari, Asgar Hussain, Azhar, Mohd., Kumar, Manoj, Rauthan, Riya, Sharma, Namrata, Aich, Meghali, Sinha, Dipanjali, Sharma, Saumya, Jain, Shivani, Ray, Arjun, Jain, Suman, Ramalingam, Sivaprakash, Maiti, Souvik, Chakraborty, Debojyoti
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800334/
https://ncbi.nlm.nih.gov/pubmed/31570623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818461116
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