Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing

Genome editing using the CRISPR/Cas9 system has been used to make precise heritable changes in the DNA of organisms. Although the widely used Streptococcus pyogenes Cas9 (SpCas9) and its engineered variants have been efficiently harnessed for numerous gene-editing applications across different platf...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Acharya, Sundaram, Mishra, Arpit, Paul, Deepanjan, Ansari, Asgar Hussain, Azhar, Mohd., Kumar, Manoj, Rauthan, Riya, Sharma, Namrata, Aich, Meghali, Sinha, Dipanjali, Sharma, Saumya, Jain, Shivani, Ray, Arjun, Jain, Suman, Ramalingam, Sivaprakash, Maiti, Souvik, Chakraborty, Debojyoti
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2019
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800334/
https://ncbi.nlm.nih.gov/pubmed/31570623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818461116
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