Postmenopausal osteoporotic fracture-associated COLIA1 variant impacts bone accretion in girls

Over the past two decades, a low frequency variant (rs1800012) within the first intron of the type I collagen alpha 1 (COLIA1) gene has been implicated in lower areal BMD (aBMD) and increased risk of osteoporotic fracture. This association is particularly strong in postmenopausal women, in whom net...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bone
Prif Awduron: Cousminer, Diana L., McCormack, Shana E., Mitchell, Jonathan A., Chesi, Alessandra, Kindler, Joseph M., Kelly, Andrea, Voight, Benjamin F., Kalkwarf, Heidi J., Lappe, Joan M., Shepherd, John A., Oberfield, Sharon E., Gilsanz, Vicente, Zemel, Babette S., Grant, Struan F. A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800229/
https://ncbi.nlm.nih.gov/pubmed/30711642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.01.026
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg