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A 3D Human Tri-Culture System Modeling Neurodegeneration and Neuroinflammation in Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by beta-amyloid (Aβ) accumulation, phosphorylated tau (p-tau) formation, hyper-activation of glial cells, and neuronal loss. The mechanisms of AD pathogenesis, however, remain poorly understood partially due to the lack of relevant human models that can comp...
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| Publicat a: | Nat Neurosci |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800152/ https://ncbi.nlm.nih.gov/pubmed/29950669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0175-4 |
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