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Targeting High Mobility Group Box-1 (HMGB1) Promotes Cell Death in Myelodysplastic Syndrome

PURPOSE: Myelodysplastic syndrome (MDS) is associated with a dysregulated innate immune system. The purpose of this study was to determine whether modulation of the innate immune system via high mobility group box-1 (HMGB1) could reduce cell viability in MDS. EXPERIMENTAL DESIGN: We quantified HMGB1...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Kam, Angel Y.F., Piryani, Sadhna O., McCall, Chad M., Park, Hee Su, Rizzieri, David A., Doan, Phuong L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800136/
https://ncbi.nlm.nih.gov/pubmed/30952643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-3517
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