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Addition of Eltrombopag to Immunosuppressive Therapy in Patients with Newly Diagnosed Aplastic Anemia

BACKGROUND: Immune-mediated destruction of hematopoietic stem cells is implicated in the pathophysiology of aplastic anemia (AA). Immunosuppressive therapy (IST) using antithymocyte globulin and cyclosporine is successful in this setting. Eltrombopag is active in refractory AA, presumably by increas...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Assi, Rita, Garcia-Manero, Guillermo, Ravandi, Farhad, Borthakur, Gautam, Daver, Naval, Jabbour, Elias, Burger, Jan, Estrov, Zeev, Dinardo, Courtney, Alvarado, Yesid, Hendrickson, Stephany, Ferrajoli, Alessandra, Wierda, William, Cortes, Jorge, Kantarjian, Hagop, Kadia, Tapan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800043/
https://ncbi.nlm.nih.gov/pubmed/30307606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31658
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