Addition of Eltrombopag to Immunosuppressive Therapy in Patients with Newly Diagnosed Aplastic Anemia

BACKGROUND: Immune-mediated destruction of hematopoietic stem cells is implicated in the pathophysiology of aplastic anemia (AA). Immunosuppressive therapy (IST) using antithymocyte globulin and cyclosporine is successful in this setting. Eltrombopag is active in refractory AA, presumably by increas...

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Veröffentlicht in:Cancer
Hauptverfasser: Assi, Rita, Garcia-Manero, Guillermo, Ravandi, Farhad, Borthakur, Gautam, Daver, Naval, Jabbour, Elias, Burger, Jan, Estrov, Zeev, Dinardo, Courtney, Alvarado, Yesid, Hendrickson, Stephany, Ferrajoli, Alessandra, Wierda, William, Cortes, Jorge, Kantarjian, Hagop, Kadia, Tapan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800043/
https://ncbi.nlm.nih.gov/pubmed/30307606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31658
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