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p53 Keeps Bystanders at the Gates
The inappropriate expansion of self-reactive “bystander” T cells can contribute to autoimmune disease. In this issue of Immunity, Watanabe et al. (2014) demonstrate that the tumor suppressor p53 prevents the cytokine-dependent proliferation of T cells in the absence of cognate antigens.
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| Publié dans: | Immunity |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6800040/ https://ncbi.nlm.nih.gov/pubmed/24837097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.05.001 |
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