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p53 Keeps Bystanders at the Gates

The inappropriate expansion of self-reactive “bystander” T cells can contribute to autoimmune disease. In this issue of Immunity, Watanabe et al. (2014) demonstrate that the tumor suppressor p53 prevents the cytokine-dependent proliferation of T cells in the absence of cognate antigens.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Immunity
Prif Awduron: Fray, Michael A., Bunnell, Stephen C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6800040/
https://ncbi.nlm.nih.gov/pubmed/24837097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.05.001
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