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3348 Structural Determinants of Neoantigen Immunogenicity for Cancer Therapy
OBJECTIVES/SPECIFIC AIMS: We are exploring the structure of the interaction between an immunogenic neoantigen and a T cell receptor (TCR) that recognizes the neoantigen while tolerating the counterpart self antigen. No structural example exists to date of how a TCR can discriminate between a neoanti...
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| Publicado no: | J Clin Transl Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6799638/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.54 |
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