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3433 Tissue Engineered Nigrostriatal Pathway as a Test-Bed for Evaluating Axonal Pathophysiology in Parkinson’s disease

OBJECTIVES/SPECIFIC AIMS: Selective loss of long-projecting neural circuitry is a common feature of many neurodegenerative diseases, such as the vulnerable nigrostriatal pathway in Parkinson’s disease (PD). Current in vitro approaches for studying disease development generally do not mimic complex a...

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發表在:J Clin Transl Sci
Main Authors: Clark, Elisia, Struzyna, Laura, Gordián-Vélez, Wisberty, Cullen, Kacy
格式: Artigo
語言:Inglês
出版: Cambridge University Press 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799488/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.60
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