Tissue engineered nigrostriatal pathway for treatment of Parkinson’s disease

The classic motor deficits of Parkinson’s disease are caused by degeneration of dopaminergic neurons in the substantia nigra pars compacta, resulting in the loss of their long-distance axonal projections that modulate the striatum. Current treatments only minimize the symptoms of this disconnection...

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Pubblicato in:J Tissue Eng Regen Med
Autori principali: Struzyna, Laura A., Browne, Kevin D., Brodnik, Zachary D., Burrell, Justin C., Harris, James P., Chen, H. Isaac, Wolf, John A., Panzer, Kate V., Lim, James, Duda, John E., España, Rodrigo A., Cullen, D. Kacy
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416379/
https://ncbi.nlm.nih.gov/pubmed/29766664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/term.2698
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