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2459 Hippocampal network disruption in early amyloid pathology

OBJECTIVES/SPECIFIC AIMS: We aim to show that amyloid accumulation in an animal model of Alzheimer’s disease leads to a preferential disruption of inhibitory parvalbumin-expressing interneurons, and the peri-neuronal nets that surround them, resulting in downstream network alterations to potentially...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Transl Sci
Prif Awduron: Caccavano, Adam, Vicini, Stefano
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cambridge University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798962/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.81
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