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2459 Hippocampal network disruption in early amyloid pathology
OBJECTIVES/SPECIFIC AIMS: We aim to show that amyloid accumulation in an animal model of Alzheimer’s disease leads to a preferential disruption of inhibitory parvalbumin-expressing interneurons, and the peri-neuronal nets that surround them, resulting in downstream network alterations to potentially...
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| Udgivet i: | J Clin Transl Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cambridge University Press
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798962/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.81 |
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