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3177 Determining mechanisms underlying hippocampal network disruption in early amyloid pathology

OBJECTIVES/SPECIFIC AIMS: Alzheimer’s disease (AD) is the leading cause of dementia, and a rapidly growing public health crisis as life expectancy increases. Two hallmark symptoms of the disease are memory impairment and the pathological accumulation of amyloid beta protein. The hippocampus is a bra...

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Publicat a:J Clin Transl Sci
Autors principals: Caccavano, Adam, Bozzelli, P. Lorenzo, Conant, Katherine, Vicini, Stefano
Format: Artigo
Idioma:Inglês
Publicat: Cambridge University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798952/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.236
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