3005 Integrin Mac-1 Potentiates Neutrophil Adhesion and NET Release in Antiphospholipid Syndrome

OBJECTIVES/SPECIFIC AIMS: While the role of antiphospholipid antibodies in activating endothelial cells has been extensively studied, the impact of these antibodies on the adhesive potential of leukocytes has received considerably less attention. Mac-1 is a heterodimeric beta-2 integrin primarily ex...

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Vydáno v:J Clin Transl Sci
Hlavní autoři: Sule, Gautam, Kelley, William J., Yalavarthi, Srilakshmi, Eniola-Adefeso, Omolola, Knight, Jason S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cambridge University Press 2019
Témata:
Basic/Translational Science/Team Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798700/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.36
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