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2043: Pharmacokinetic prediction of paclitaxel-induced peripheral neuropathy
OBJECTIVES/SPECIFIC AIMS: Peripheral neuropathy is the dose limiting toxicity of paclitaxel treatment. Paclitaxel pharmacokinetics (PK), specifically the Cmax and amount of time the concentration remains above 0.05 µM (Tc>0.05), have been associated with occurrence of severe, clinician-documented...
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| Pubblicato in: | J Clin Transl Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cambridge University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6798474/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2017.114 |
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