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Iron Accumulates in Retinal Vascular Endothelial Cells But Has Minimal Retinal Penetration After IP Iron Dextran Injection in Mice

PURPOSE: Iron supplementation therapy is used for iron-deficiency anemia but has been associated with macular degeneration in a 43-year-old patient. Iron entry into the neurosensory retina (NSR) can be toxic. It is important to determine conditions under which serum iron might cross the blood retina...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Invest Ophthalmol Vis Sci
Hauptverfasser: Shu, Wanting, Baumann, Bailey H., Song, Ying, Liu, Yingrui, Wu, Xingwei, Dunaief, Joshua L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Association for Research in Vision and Ophthalmology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798310/
https://ncbi.nlm.nih.gov/pubmed/31634395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.19-28250
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