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In Vitro Double-Stranded RNA Synthesis by Rotavirus Polymerase Mutants with Lesions at Core Shell Contact Sites

The rotavirus polymerase VP1 mediates all stages of viral RNA synthesis within the confines of subviral particles and while associated with the core shell protein VP2. Transcription (positive-strand RNA [+RNA] synthesis) by VP1 occurs within double-layered particles (DLPs), while genome replication...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Steger, Courtney L., Brown, Mackenzie L., Sullivan, Owen M., Boudreaux, Crystal E., Cohen, Courtney A., LaConte, Leslie E. W., McDonald, Sarah M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798093/
https://ncbi.nlm.nih.gov/pubmed/31341048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01049-19
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