Global Dynamics of Yeast Hsp90 Middle and C-Terminal Dimer Studied by Advanced Sampling Simulations

The Hsp90 protein complex is one of the most abundant molecular chaperone proteins that assists in folding of a variety of client proteins. During its functional cycle it undergoes large domain rearrangements coupled to the hydrolysis of ATP and association or dissociation of domain interfaces. In o...

Full description

Saved in:
Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Kandzia, Florian, Ostermeir, Katja, Zacharias, Martin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798034/
https://ncbi.nlm.nih.gov/pubmed/31681792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00093
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items