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Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2
Proper spindle formation and accurate chromosome segregation are essential for ensuring mitotic fidelity. Phosphatase and tensin homolog (PTEN) is a multifunctional protein, which is able to maintain the stability of the genome and chromosomes. The present study described an essential role of PTEN i...
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| Publicat a: | Mol Med Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
D.A. Spandidos
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797992/ https://ncbi.nlm.nih.gov/pubmed/31545428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10668 |
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