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Deficiency of PTEN leads to aberrant chromosome segregation through downregulation of MAD2

Proper spindle formation and accurate chromosome segregation are essential for ensuring mitotic fidelity. Phosphatase and tensin homolog (PTEN) is a multifunctional protein, which is able to maintain the stability of the genome and chromosomes. The present study described an essential role of PTEN i...

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Detalles Bibliográficos
Publicado en:Mol Med Rep
Main Authors: Sun, Zhuo, Lu, Jinqi, Wu, Muyu, Li, Mingyan, Bai, Lu, Shi, Zhenduo, Hao, Lin, Wu, Yongping
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797992/
https://ncbi.nlm.nih.gov/pubmed/31545428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10668
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