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House dust mite induces Sonic hedgehog signaling that mediates epithelial-mesenchymal transition in human bronchial epithelial cells

Epithelial-mesenchymal transition (EMT) provides a valuable source of fibroblasts that produce extracellular matrix in airway walls. The Sonic hedgehog (SHH) signaling pathway plays an essential role in regulating tissue turnover and homeostasis. SHH is strikingly upregulated in the bronchial epithe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med Rep
Hauptverfasser: Zou, Yimin, Song, Wenjuan, Zhou, Lingxiao, Mao, Yanxiong, Hong, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797970/
https://ncbi.nlm.nih.gov/pubmed/31702025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10707
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