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House dust mite induces Sonic hedgehog signaling that mediates epithelial-mesenchymal transition in human bronchial epithelial cells

Epithelial-mesenchymal transition (EMT) provides a valuable source of fibroblasts that produce extracellular matrix in airway walls. The Sonic hedgehog (SHH) signaling pathway plays an essential role in regulating tissue turnover and homeostasis. SHH is strikingly upregulated in the bronchial epithe...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Zou, Yimin, Song, Wenjuan, Zhou, Lingxiao, Mao, Yanxiong, Hong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797970/
https://ncbi.nlm.nih.gov/pubmed/31702025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10707
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