Human single-chain antibodies that neutralize Pseudomonas aeruginosa-exotoxin A-mediated cellular apoptosis

Targeting bacterial virulence factors directly provides a new paradigm for the intervention and treatment of bacterial diseases. Pseudomonas aeruginosa produces a myriad of virulence factors to cause fatal diseases in humans. In this study, human single-chain antibodies (HuscFvs) that bound to P. ae...

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Publicado en:Sci Rep
Autores principales: Santajit, Sirijan, Seesuay, Watee, Mahasongkram, Kodchakorn, Sookrung, Nitat, Ampawong, Sumate, Reamtong, Onrapak, Diraphat, Pornphan, Chaicumpa, Wanpen, Indrawattana, Nitaya
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797803/
https://ncbi.nlm.nih.gov/pubmed/31624289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51089-w
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