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MDT-28/PLIN-1 mediates lipid droplet-microtubule interaction via DLC-1 in Caenorhabditis elegans

Ectopic lipid accumulation in lipid droplets (LD) has been linked to many metabolic diseases. In this study, DHS-3::GFP was used as a LD marker in C. elegans and a forward genetic screen was carried out to find novel LD regulators. There were 140 mutant alleles identified which were divided into fou...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Xie, Kang, Zhang, Peng, Na, Huimin, Liu, Yangli, Zhang, Hong, Liu, Pingsheng
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797801/
https://ncbi.nlm.nih.gov/pubmed/31624276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51399-z
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