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Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans

Dietary fat accumulates in lipid droplets or endolysosomal compartments that undergo selective expansion under normal or pathophysiological conditions. We find that genetic defects in a peroxisomal β-oxidation pathway cause size expansion in lipid droplets that are distinct from the lysosome-related...

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Bibliografske podrobnosti
Main Authors: Zhang, Shaobing O., Box, Andrew C., Xu, Ningyi, Le Men, Johan, Yu, Jingyi, Guo, Fengli, Trimble, Rhonda, Mak, Ho Yi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842062/
https://ncbi.nlm.nih.gov/pubmed/20176933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912308107
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