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Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis

The tissue inhibitor of metalloproteinase-3 (TIMP3) is the only member of the TIMP family that binds to the extracellular matrix and suppresses cancer cell growth, angiogenesis, migration, and invasion. However, whether the abnormal expression and promoter methylation of TIMP3 facilitates oral cance...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cell Death Dis
मुख्य लेखकों: Su, Chun-Wen, Chang, Yu-Chao, Chien, Ming-Hsien, Hsieh, Yi-Hsien, Chen, Mu-Kuan, Lin, Chiao-Wen, Yang, Shun-Fa
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797751/
https://ncbi.nlm.nih.gov/pubmed/31624299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2016-0
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