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Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis
The tissue inhibitor of metalloproteinase-3 (TIMP3) is the only member of the TIMP family that binds to the extracellular matrix and suppresses cancer cell growth, angiogenesis, migration, and invasion. However, whether the abnormal expression and promoter methylation of TIMP3 facilitates oral cance...
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| Publicat a: | Cell Death Dis |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797751/ https://ncbi.nlm.nih.gov/pubmed/31624299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2016-0 |
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