Salsolinol Attenuates Doxorubicin-Induced Chronic Heart Failure in Rats and Improves Mitochondrial Function in H9c2 Cardiomyocytes

Backgrounds: Salsolinol (SAL), a plant-based isoquinoline alkaloid, was initially isolated from Aconiti Lateralis Radix Praeparata (ALRP) and identified as the active cardiotonic component of ALRP. This study was aimed to explore the therapeutic effect and mechanism by which SAL attenuates doxorubic...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Wen, Jianxia, Zhang, Lu, Liu, Honghong, Wang, Jiabo, Li, Jianyu, Yang, Yuxue, Wang, Yingying, Cai, Huadan, Li, Ruisheng, Zhao, Yanling
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797600/
https://ncbi.nlm.nih.gov/pubmed/31680945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01135
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