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Natural Killer Cells in Myeloid Malignancies: Immune Surveillance, NK Cell Dysfunction, and Pharmacological Opportunities to Bolster the Endogenous NK Cells

Natural killer (NK) cells are large granular lymphocytes involved in our defense against certain virus-infected and malignant cells. In contrast to T cells, NK cells elicit rapid anti-tumor responses based on signals from activating and inhibitory cell surface receptors. They also lyse target cells...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Carlsten, Mattias, Järås, Marcus
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797594/
https://ncbi.nlm.nih.gov/pubmed/31681270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02357
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