CRM197 reverses paclitaxel resistance by inhibiting the NAC‐1/Gadd45 pathway in paclitaxel‐resistant ovarian cancer cells

Heparin‐binding epidermal growth factor‐like growth factor (HB‐EGF) is a new promising target for the treatment of ovarian cancer. Our previous study showed that cross‐reacting material 197 (CRM197), a specific HB‐EGF inhibitor, significantly reverses resistance against paclitaxel in paclitaxel‐resi...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Tang, Xiao‐han, Li, Hui, Zheng, Xiu‐shuang, Lu, Mei‐song, An, Yuan, Zhang, Xiao‐lei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797568/
https://ncbi.nlm.nih.gov/pubmed/31490008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2512
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