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TEM8/ANTXR1-specific CAR T cells mediate toxicity in vivo
Engineering T-cells to express receptors specific for antigens present on tumour tissue is proving a highly effective treatment for some leukaemias. However, extending this to solid tumours requires antigens that can be safely and effectively targeted. TEM8, a marker overexpressed on the vasculature...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797195/ https://ncbi.nlm.nih.gov/pubmed/31622431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224015 |
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