Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer featured with high intra-tumoral heterogeneity and poor prognosis. To comprehensively delineate the PDAC intra-tumoral heterogeneity and the underlying mechanism for PDAC progression, we employed single-cell RNA-seq...

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Veröffentlicht in:Cell Res
Hauptverfasser: Peng, Junya, Sun, Bao-Fa, Chen, Chuan-Yuan, Zhou, Jia-Yi, Chen, Yu-Sheng, Chen, Hao, Liu, Lulu, Huang, Dan, Jiang, Jialin, Cui, Guan-Shen, Yang, Ying, Wang, Wenze, Guo, Dan, Dai, Menghua, Guo, Junchao, Zhang, Taiping, Liao, Quan, Liu, Yi, Zhao, Yong-Liang, Han, Da-Li, Zhao, Yupei, Yang, Yun-Gui, Wu, Wenming
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796938/
https://ncbi.nlm.nih.gov/pubmed/31273297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0195-y
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