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Interferon-inducible cytoplasmic lncLrrc55-AS promotes antiviral innate responses by strengthening IRF3 phosphorylation

Type I interferon (IFN-I) production is efficiently induced to ensure a potent innate immune response to viral infection. How this response can be enhanced, however, remains to be explored. Here, we identify a new cytoplasmic long non-coding RNA (lncRNA), lncLrrc55-AS, that drives a positive feedbac...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Zhou, Yumei, Li, Mengxuan, Xue, Yiquan, Li, Zhiqing, Wen, Weitao, Liu, Xingguang, Ma, Yuanwu, Zhang, Lianfeng, Shen, Zhongyang, Cao, Xuetao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796909/
https://ncbi.nlm.nih.gov/pubmed/31213650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0193-0
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