Intragenic antagonistic roles of protein and circRNA in tumorigenesis

circRNAs arise from back splicing events during mRNA processing, and when deregulated can play an active role in cancer. Here we characterize a new circRNA (circPOK) encoded by the Zbtb7a gene (also kown as POKEMON, LRF) in the context of mesenchymal tumor progression. circPOK functions as a non-cod...

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Pubblicato in:Cell Res
Autori principali: Guarnerio, Jlenia, Zhang, Yang, Cheloni, Giulia, Panella, Riccardo, Mae Katon, Jesse, Simpson, Mark, Matsumoto, Akinobu, Papa, Antonella, Loretelli, Cristian, Petri, Andreas, Kauppinen, Sakari, Garbutt, Cassandra, Petur Nielsen, Gunnlaugur, Deshpande, Vikram, Castillo-Martin, Mireia, Cordon-Cardo, Carlos, Dimitrios, Spentzos, Clohessy, John G., Batish, Mona, Pandolfi, Pier Paolo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796857/
https://ncbi.nlm.nih.gov/pubmed/31209250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-019-0192-1
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