Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activation

BACKGROUND: The objective of the current study was to study the molecular mechanism(s) underlying cardiac troponin I autoantibody (cTnIAAb) binding to cardiomyocyte and resultant myocardial damage/dysfunction. METHODS: cTnIAAb was purified from serum of 10 acute myocardial infarction (AMI) patients...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wu, Yu, Qin, Yang-hua, Liu, Yang, Zhu, Li, Zhao, Xian-xian, Liu, Yao-yang, Luo, Shi-wen, Tang, Gu-sheng, Shen, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796505/
https://ncbi.nlm.nih.gov/pubmed/31474552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.08.045
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